Authors: Paula Franklin and Gabrielle Gimenes Lima (FEBRAF, Brazil) @PaulaFranklin Human papillomavirus (HPV) is a DNA virus belonging to the Papoviridae family and the genus Papillomavirus.4 It presents tropism by epithelial cells, is the cause of one of the most common infections in the world, and is also related to the occurrence of cervical cancer Uterus. 4 5 The most common clinical manifestations of infection by such a virus are the appearance of warts, which mainly affect the skin of the extremities, mucosa, genital skin, and oral and laryngeal mucosa. 4 There is no specific treatment to eliminate human papillomavirus, being done only the treatment of such warts by laser, electrocauterization, trichloroacetic acid (ATA), and drugs that improve the body's defense system. ³ According to the World Health Organization, pharmaceutical assistance is the set of actions aimed at the promotion, protection, and recovery of health, both individual and collective, with the medicine as an essential input and aiming at access to its rational use.¹ Such assistance can be done in cases where HPV causes cervical cancer, in which case treatments such as chemotherapy and radiotherapy are used. 6 Chemotherapy is based on the use of drugs that act at the cellular level, interfering in the process of cell growth and division, to treat malignant neoplasms. As important as the diagnosis, is the adherence to the use of drugs by patients, which may be lower in cases of neoplasia. Thus, pharmaceutical assistance can act to guide the patient on the correct use of medicines. 6 REFERENCES ORGANIZAÇÃO MUNDIAL DA SAÚDE. Assistência Farmacêutica. Disponível em < https://www.paho.org/bra/index.php?option=com_content&view=article&id=356:assistencia-farmaceutica&Itemid=454#: :text=Assist%C3%AAncia%20Farmac%C3%AAutica%20%C3%A9%20o%20conjunto,e%20ao%20seu%20uso%20racional .>. Acesso em 05 de março de 2021. PEREIRA, Leonardo Régis Leira; FREITAS, Osvaldo de. A evolução da Atenção Farmacêutica e a perspectiva para o Brasil. Rev. Bras. Cienc. Farm., São Paulo , v. 44, n. 4, p. 601-612, Dec. 2008. Available from < http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-93322008000400006&lng=en&nrm=iso >. access on 05 Mar. 2021. https://doi.org/10.1590/S1516-93322008000400006 INSTITUTO NACIONAL DO CANCER. Disponível em: https://www.inca.gov.br/ LETO, Maria das Graças Pereira et al. Infecção pelo papilomavírus humano: etiopatogenia, biologia molecular e manifestações clínicas. An. Bras. Dermatol., Rio de Janeiro, v.86, n.2, p.306-317, Apr. 2011. Available from < http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000200014&lng=en&nrm=iso >. Access on 06 Mar. 2021. https://doi.org/10.1590/S0365-05962011000200014 . Ayres ARG, Silva GA, Teixeira MTB, Duque KCD, Machado MLSM, Gamarra CJ, et al. Infecção por HPV em mulheres atendidas pela Estratégia Saúde da Família. Rev Saude Publica. 2017;51:92. Disponível em http://www.rsp.fsp.usp.br/wp-content/uploads/articles_xml/0034-8910-rsp-S1518-87872017051000065/0034-8910-rsp-S1518-87872017051000065-pt.x67403.pdf . Acesso em 05 de março de 2021. DANTAS, Mariana Pedrollo. Atenção Farmacêutica para pacientes com câncer do colo do útero em tratamento quimioterápico ambulatorial. Disponível em: https://app.uff.br/riuff/bitstream/1/12465/1/TCC%20MARIANA%20DANTAS%20CORRIGIDO%20APOS%20BANCA%20%281%29.pdf . Acesso em 05 de março de 2021.

Pharmaceutical Assistance in Cases of HPV

gbriellegimenes

Authors: Paula Franklin and Gabrielle Gimenes Lima (FEBRAF, Brazil)
@PaulaFranklin
Human papillomavirus (HPV) is a DNA virus belonging to the Papoviridae family and the genus Papillomavirus.4 It presents tropism by epithelial cells, is the cause of one of the most common infections in the world, and is also related to the occurrence of cervical cancer Uterus. 4 5
The most common clinical manifestations of infection by such a virus are the appearance of warts, which mainly affect the skin of the extremities, mucosa, genital skin, and oral and laryngeal mucosa. 4 There is no specific treatment to eliminate human papillomavirus, being done only the treatment of such warts by laser, electrocauterization, trichloroacetic acid (ATA), and drugs that improve the body's defense system. ³
According to the World Health Organization, pharmaceutical assistance is the set of actions aimed at the promotion, protection, and recovery of health, both individual and collective, with the medicine as an essential input and aiming at access to its rational use.¹ Such assistance can be done in cases where HPV causes cervical cancer, in which case treatments such as chemotherapy and radiotherapy are used. 6
Chemotherapy is based on the use of drugs that act at the cellular level, interfering in the process of cell growth and division, to treat malignant neoplasms. As important as the diagnosis, is the adherence to the use of drugs by patients, which may be lower in cases of neoplasia. Thus, pharmaceutical assistance can act to guide the patient on the correct use of medicines. 6

REFERENCES

ORGANIZAÇÃO MUNDIAL DA SAÚDE. Assistência Farmacêutica. Disponível em < https://www.paho.org/bra/index.php?option=com_content&view=article&id=356:assistencia-farmaceutica&Itemid=454#:_{:text=Assist%C3%AAncia%20Farmac%C3%AAutica%20%C3%A9%20o%20conjunto,e%20ao%20seu%20uso%20racional}.>. Acesso em 05 de março de 2021.
PEREIRA, Leonardo Régis Leira; FREITAS, Osvaldo de. A evolução da Atenção Farmacêutica e a perspectiva para o Brasil. Rev. Bras. Cienc. Farm., São Paulo , v. 44, n. 4, p. 601-612, Dec. 2008. Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-93322008000400006&lng=en&nrm=iso>. access on 05 Mar. 2021. https://doi.org/10.1590/S1516-93322008000400006
INSTITUTO NACIONAL DO CANCER. Disponível em: https://www.inca.gov.br/
LETO, Maria das Graças Pereira et al. Infecção pelo papilomavírus humano: etiopatogenia, biologia molecular e manifestações clínicas. An. Bras. Dermatol., Rio de Janeiro, v.86, n.2, p.306-317, Apr. 2011. Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962011000200014&lng=en&nrm=iso>. Access on 06 Mar. 2021. https://doi.org/10.1590/S0365-05962011000200014.
Ayres ARG, Silva GA, Teixeira MTB, Duque KCD, Machado MLSM, Gamarra CJ, et al. Infecção por HPV em mulheres atendidas pela Estratégia Saúde da Família. Rev Saude Publica. 2017;51:92. Disponível em http://www.rsp.fsp.usp.br/wp-content/uploads/articles_xml/0034-8910-rsp-S1518-87872017051000065/0034-8910-rsp-S1518-87872017051000065-pt.x67403.pdf. Acesso em 05 de março de 2021.
DANTAS, Mariana Pedrollo. Atenção Farmacêutica para pacientes com câncer do colo do útero em tratamento quimioterápico ambulatorial. Disponível em: https://app.uff.br/riuff/bitstream/1/12465/1/TCC%20MARIANA%20DANTAS%20CORRIGIDO%20APOS%20BANCA%20%281%29.pdf. Acesso em 05 de março de 2021.