Drug delivery is the method or process of administering a pharmaceutical compound in order to achieve a therapeutic effect in humans or animals.
Nanotechnology drug delivery applications
The use of nanotechnological materials as well as forming delivery systems from nanoscale molecules such as liposomes. The application of nanotechnology for drug delivery provides the potential for enhanced treatments with target delivery and fewer side effects.
Nanoparticle-based drug delivery systems, such as liposomes, micelles, nanoemulsions, nanocapsules, solid lipid nanoparticles, magnetic nanoparticles, and albumin nanoparticles have great potential to be therapeutically effective systems for diseases. This delivery system has great potential to overcome some of the barriers to efficient targeting of cells and molecules in inflammation and cancer. It now provides the possibility to overcome problems of drug resistance in target cells and to facilitate movements of drugs across the blood-brain barrier.
The nanoparticulates drug delivery system provides plenty of advantages over conventional dosage forms. The reduced toxicity, enhanced bio-distribution and improved patient compliance.
The challenge at hand is the proper characterization of molecular targets and ensuring that these nanoparticles are directed toward the targeted organs to prevent adverse effects on unaffected tissues. To take more nanotechnology-based products into the clinic, it is necessary to address the risk issues simultaneously, including any risks resulting from the nanoscale properties of the materials used.
Proper ejection of remaining nano particles from the body after the drug has been delivered to the target place.
One of the issues that affect the application of nanotechnology in the drug delivery is the stability problems of nanoparticles. Nanoparticles have high free energies due to their sizes, this causes aggregation and agglomeration.